Identification of a type I nitroreductase gene in non-virulent Trypanosoma rangeli
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منابع مشابه
Identification of a type I nitroreductase gene in non-virulent Trypanosoma rangeli
Trypanosomatid type I nitroreductases (NTRs), i.e., mitochondrial enzymes that metabolise nitroaromatic pro-drugs, are essential for parasite growth, infection, and survival. Here, a type I NTR of non-virulent protozoan Trypanosoma rangeli is described and compared to those of other trypanosomatids. The NTR gene was isolated from KP1(+) and KP1(-) strains, and its corresponding transcript and 5...
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ژورنال
عنوان ژورنال: Memórias do Instituto Oswaldo Cruz
سال: 2017
ISSN: 0074-0276
DOI: 10.1590/0074-02760160532